Anfield | Monday 9 August 2021 at 19:00 UK local time
| Liverpool | 3 | - | 1 | Osasuna |
| Caoimhin Kelleher |
| Neco Williams |
| Joe Gomez |
| Ibrahima Konaté |
| Kostas Tsimikas |
| Fabinho Tavares |
| Alex Oxlade-Chamberlain |
| Curtis Jones |
| Kaide Gordon |
| Takumi Minamino |
| Roberto Firmino |
| Curtis Jones replaced by Ben Woodburn 30′ |
| Kaide Gordon replaced by Divock Origi 46′ |
| Joe Gomez replaced by Rhys Williams 59′ |
| Fabinho Tavares replaced by Thiago Alcantara 59′ |
| Roberto Firmino replaced by Leighton Clarkson 59′ |
| Kostas Tsimikas replaced by Owen Beck 71′ |
| Takumi Minamino replaced by Jordan Henderson 71′ |
| Neco Williams replaced by Conor Bradley 80′ |
| Ibrahima Konaté replaced by Ben Davies 80′ |
| Loris Karius |
| Harvey Davies |
| Jake Cain |
Opposition
Lineup 1st half: Perez, Areso, Cruz, U.Garcia, D.Garcia, Oier, Torres, Perez, Torro, Barbero, Avila
Lineup 2nd half: Herrera, Areso (Vidal 61), Cruz (R. Garcia 61), Ramalho, Grau, Oroz, Torres (Barja 61), Dufur, Martinez, Kiki, Budimir
Unused subs: Brasanac
Goal: Kiki 70:
The scheduled kick off time of 19.00 was delayed 15 minutes due to crowd congestion.
